In Situ Carcinomas of the Breast

In Situ Carcinomas of the Breast

DCIS (Ductal Carcinoma In Situ)

DCIS is commonly identified in association with micro-calcifications seen on a mammogram. These lesions are often not palpable and may be identified commonly during routine screening breast imaging.

Cells are similar to those of invasive carcinomas but are confined to ductal structures within the breast parenchyma. Such lesions may be located within areas of Invasive carcinoma, however can be identified as in situ lesions only.

Characterised as low, intermediate or high grade.

Treatment requires complete excision (with clear margins) in addition to adjuvant radiation therapy (for breast conserving surgery).

LCIS (Lobular Carcinoma In Situ)

Considered a marker of increased risk of breast cancer.

Pleomorphic LCIS

May actually progress into invasive Lobular Carcinoma and therefore is treated with excision.